Wednesday, 24 July 2013
Oligomers Help Us Keep Our Memories
A protein whose molecules have the special ability to stack on top of one another, somewhat like egg cartons, and thus form short, highly stable chains (oligomers), may well play a key role in the mechanisms by which we maintain lasting memories.
Indeed, there is always something magical about remembering something that you haven’t thought about in years. But physically speaking, in what form is the corresponding memory trace maintained in your brain over all that time? Neurobiologists know that the whole process occurs in the synapses (the plastic connections between neurons) and have described molecular mechanisms such as long-term potentiation that partly explain this plasticity. (more…)
Memory and the Brain, Mental Disorders | Comments Closed
Monday, 15 July 2013
The Brain’s Default Network
What does the human brain do when it’s not doing anything in particular? At first glance, this question might seem of little interest, and for many years most brain researchers paid little attention to it. But over the past 10 years or so, it has become one of the hottest and most intriguing research topics in neuroscience: the activity of the brain’s default network.
The default network is a set of areas in the brain that are connected to one another, in some cases across large distances (in terms of the brain’s size). They are activated preferentially when the individual is not performing any specific task. Scientists do not yet know exactly what purpose this default brain activity serves. But they do already know that the areas involved in the default network are more active when our minds are wandering (when we have “our heads in the clouds”), when we are evoking personal memories, and when we are trying to imagine ourselves in future situations or to understand someone else’s point of view. (more…)
The Emergence of Consciousness | Comments Closed
Thursday, 4 July 2013
Links on Avoiding Pain
This week, as I have before in this blog, I am posting a set of new links to other web sites that discuss a subject covered in The Brain from Top to Bottom. The subject this week is the sub-topic “Avoiding Pain”, under the topic “Pleasure and Pain”. For each link, I also provide a brief description of the content on the site in question. (more…)
Pleasure and Pain | Comments Closed
Monday, 24 June 2013
The Complementarity of the Brain’s Two Hemispheres
Einstein said that intuition is a gift, and rationality is its servant. But in another RSA Animate lecture to which we provide a link this week, about the specialization of the two hemispheres of the human brain, psychiatrist and author Iain McGilchrist says that we have created a society that honours the servant but has forgotten the gift. (more…)
From Thought to Language | Comments Closed
Tuesday, 18 June 2013
Proteins That Guide the Wiring of the Brain
The human brain has millions of times more connections between its neurons than the number of genes (roughly 20 000 to 25 000) in the DNA of these cells. And yet, when the brain is developing, the tips of the axons of its growing neurons act like veritable homing devices, successfully seeking out their specific targets in the complex molecular soup that constitutes the extracellular environment.
Scientists have long known that these targets produce molecules that are detected by receptors on the axons’ growth cones and guide them to their targets. But only recently did a team at the Salk Institute in California discover how just a handful of genes enable the guidance processes by which the brain’s complex wiring is established. (more…)
How the Mind Develops | Comments Closed
