After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen





Thursday, 16 August 2018
Human Brain Networks Operate on a Unimodal/Multimodal Gradient

This week I’d like to tell you about an article published in the journal PNAS in 2016. It is of interest because it does something that is extremely valuable in the realm of science: it shows how two bodies of data converge into a single phenomenon and thereby helps us to understand some things that were less clear before. Let me explain.

The article, by Daniel S. Margulies and no fewer than 11 co-authors, is entitled “ Situating the default-mode network along a principal gradient of macroscale cortical organization”. In slightly simpler terms, their study involved situating the brain’s default mode network along a large-scale organizational gradient within the cerebral cortex. Okay, let me explain further. (more…)

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